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Frymoyer A, Joshi NS, Allan JM, Cohen RS, Aby JL, Kim JL, Benitz WE, Gupta A. Sustainability of a Clinical Examination-Based Approach for Ascertainment of Early-Onset Sepsis in Late Preterm and Term Neonates. J Pediatr. 2020 Oct;225:263-268. doi: 10.1016/j.jpeds.2020.05.055. Epub 2020 Jun 5. PMID: 32511960.

We demonstrated the sustained impact over a 5-year period of a clinical examination-based approach to identification of early-onset sepsis in late preterm and term neonates at our hospital. To date, more than 20 000 neonates have been safely managed using this approach, resulting in a 63% reduction in antibiotic use.

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