Cavaliere AF, Marchi L, Aquilini D, Brunelli T, Vasarri PL. Passive Immunity in Newborn from SARS-CoV-2 Infected Mother. J Med Virol. 2020 Oct 19. doi: 10.1002/jmv.26609. Epub ahead of print. PMID: 33073377.
Background: SARS-CoV-2 vertical transmission is an open issue. Recent reports call into question in utero or peripartum viral transmission to the offspring. Few data are available on IgG and/or IgM in newborn. Insufficient evidence is available regarding passive immunity in neonates born from SARS-CoV-2 infected women.
Case: We report a case of a neonate showing the presence of blood specific IgG and the absence of IgM and negative nasopharyngeal swab. He was born from an asymptomatic SARS-CoV-2 infected mother with positive IgG and IgM.