Tusor N, De Cunto A, Basma Y, Klein JL, et al. Ventilator-associated pneumonia in neonates: the role of point of care lung ultrasound. Eur J Pediatr. 2020 Jun 26. pii: 10.1007/s00431-020-03710.
No consensus exists regarding the definition of ventilator-associated pneumonia (VAP) in neonates and reliability of chest X-ray (CXR) is low. Lung ultrasound (LU) is a potential alternative diagnostic tool. The
Wolf M, Diehl T, Zanni S, Singer D, et al. Indoor Climate and Air Quality in a Neonatal Intensive Care Unit. Neonatology. 2020 Jun 30:1-7. doi: 10.1159/000508108.
Introduction and objective: The skin and respiratory system of premature neonates are in permanent contact with indoor room air. We longitudinally analyzed the room air climate and quality in neonatal intensive
Xie W, Wang X, Huang R, Chen Y, et al. Assessment of four pain scales for evaluating procedural pain in premature infants undergoing heel blood collection. Pediatr Res. 2020 Jun 29. pii: 10.1038/s41390-020-1034.
Background: Procedural pain is underestimated in hospitalized preterm infants. The aim of this study was to assess the reliability, validity, and clinical utility of the Neonatal Facial Coding System (NFCS), Douleur
Maheshwari A. Role of platelets in neonatal necrotizing enterocolitis. Pediatr Res. 2020 Jun 29. pii: 10.1038/s41390-020-1038.
Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature infants and is a leading cause of morbidity and mortality in infants born between 23 and 28 weeks of gestation.
Berglund SK, Chmielewska AM, Domellof M, Andersson O, et al. Hepcidin is a relevant iron status indicator in infancy: results from a randomized trial of early vs. delayed cord clamping. Pediatr Res. 2020 Jul 1. pii: 10.1038/s41390-020-1045.
Background: We aimed to evaluate whether serum hepcidin is a useful indicator of iron status in infants. Methods: Term infants (n = 400) were randomized to delayed (≥180 s) or early (≤10
Thoguluva Chandrasekar V, Venkatesalu B, Patel HK, Spadaccini M, Manteuffel J, Ramesh M. Systematic review and meta-analysis of effectiveness of treatment options against SARS-CoV-2 infection [published online ahead of print, 2020 Jul 15]. J Med Virol. 2020;10.1002/jmv.26302. doi:10.1002/jmv.26302
Treatment options for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) are limited with no clarity on efficacy and safety profiles. We performed a systematic review and meta-analysis of studies on patients
Skipper CP, Pastick KA, Engen NW, et al. Hydroxychloroquine in Non hospitalized Adults With Early COVID-19: A Randomized Trial [published online ahead of print, 2020 Jul 16]. Ann Intern Med. 2020;10.7326/M20-4207. doi:10.7326/M20-4207
Background: No effective oral therapy exists for early coronavirus disease 2019 (COVID-19). Objective: To investigate whether hydroxychloroquine could reduce COVID-19 severity in adult outpatients. Design: Randomized, double-blind, placebo-controlled trial conducted
Ok F, Erdogan O, Durmus E, Carkci S, Canik A. Predictive values of blood urea nitrogen/creatinine ratio and other routine blood parameters on disease severity and survival of COVID-19 patients [published online ahead of print, 2020 Jul 14]. J Med Virol. 2020;10.1002/jmv.26300. doi:10.1002/jmv.26300
We aimed to examine independent predictive factors for the severity and survival of COVID-19 disease, from routine blood parameters, especially the blood urea nitrogen (BUN)/creatinine (Cr) ratio. A total of
Mitjà O, Corbacho-Monné M, Ubals M, et al. Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial [published online ahead of print, 2020 Jul 16]. Clin Infect Dis. 2020;ciaa1009. doi:10.1093/cid/ciaa1009
Background: No therapeutics have yet been proven effective for the treatment of mild-illness caused by SARS-CoV-2. We aimed to determine whether early treatment with hydroxychloroquine (HCQ) would be more efficacious