Eason J, Ward H, Danko O, Richardson K, Vaitkute R, McKeon-Carter R. Early-onset sepsis: can we screen fewer babies safely? Arch Dis Child. 2021 Jan;106(1):86-88. doi: 10.1136/archdischild-2019-317047. Epub 2019 Nov 2. PMID: 31678929.
Background: Over the past 2-3 years at the Southwest Peninsula tertiary neonatal unit in Plymouth, the authors have observed an increase in the number of clinically well term infants being
Salerno SN, Liao Y, Jackson W, Greenberg RG, McKinzie CJ, McCallister A, Benjamin DK, Laughon MM, Sanderson K, Clark RH, Gonzalez D. Association between Nephrotoxic Drug Combinations and Acute Kidney Injury in the Neonatal Intensive Care Unit. J Pediatr. 2021 Jan;228:213-219. doi: 10.1016/j.jpeds.2020.08.035. Epub 2020 Aug 17. PMID: 32818481; PMCID: PMC7752849.
Objective: To determine the incidence of acute kidney injury (AKI) in infants exposed to nephrotoxic drug combinations admitted to 268 neonatal intensive care units managed by the Pediatrix Medical Group. Study
Saugstad OD, Robertson NJ, Vento M. A critical review of the 2020 International Liaison Committee on Resuscitation treatment recommendations for resuscitating the newly born infant. Acta Paediatr. 2021 Jan 8. doi: 10.1111/apa.15754. Epub ahead of print. PMID: 33417251.
The 2020 recommendations from the International Liaison Committee on Resuscitation is an improved version of the 2015 version. The algorithm and 15 procedures are unchanged from 2015, but there are
Kaluarachchi DC, Nicksic VM, Allen DB, Eickhoff JC, Dawe SJ, Baker MW. Thyroid-stimulating hormone reference ranges for moderate-to-late preterm infants. J Perinatol. 2020 Dec 5. doi: 10.1038/s41372-020-00895-6. Epub ahead of print. PMID: 33279944.
Background: Identifying congenital hypothyroidism through newborn screening (NBS) is higher among moderate-to-late preterm (MLPT) infants. Currently, the same thyroid-stimulating hormone (TSH) cutoffs are used for term and preterm infants. TSH
Arakawa A, Ichikawa H, Kubo T, Motoi N, Kumamoto T, Nakajima M, Yonemori K, Noguchi E, Sunami K, Shiraishi K, Kakishima H, Yoshida H, Hishiki T, Kawakubo N, Kuroda T, Kiyokawa T, Yamada K, Yanaihara N, Takahashi K, Okamoto A, Hirabayashi S, Hasegawa D, Manabe A, Ono K, Matsuoka M, Arai Y, Togashi Y, Shibata T, Nishikawa H, Aoki K, Yamamoto N, Kohno T, Ogawa C. Vaginal Transmission of Cancer from Mothers with Cervical Cancer to Infants. N Engl J Med. 2021 Jan 7;384(1):42-50. doi: 10.1056/NEJMoa2030391. PMID: 33406329.
Two cases of pediatric lung cancer (in 23-month-old and 6-year-old boys) resulting from mother-to-infant transmission of uterine cervical tumors were incidentally detected during routine next-generation sequencing of paired samples of
Santos Silva E, Moreira Silva H, Catarino C, Dias CC, Santos-Silva A, Lopes AI. Neonatal cholestasis: development of a diagnostic decision algorithm from multivariate predictive models. Eur J Pediatr. 2021 Jan 7. doi: 10.1007/s00431-020-03886-z. Epub ahead of print. PMID: 33410939.
Despite the recent advances involving molecular studies, the neonatal cholestasis (NC) diagnosis still relays on the expertise of medical teams. Our aim was to develop models of etiological diagnosis and
Han D, Khadka A, McConnell M, Cohen J. Association of Unexpected Newborn Deaths With Changes in Obstetric and Neonatal Process of Care. JAMA Netw Open. 2020 Dec 1;3(12):e2024589. doi: 10.1001/jamanetworkopen.2020.24589. PMID: 33284335.
Importance: The death of a healthy term infant may signal patient safety and quality issues. Various initiatives aim to encourage clinicians to learn from these events, but little evidence exists
Stegeman I, Ochodo EA, Guleid F, Holtman GA, Yang B, Davenport C, Deeks JJ, Dinnes J, Dittrich S, Emperador D, Hooft L, Spijker R, Takwoingi Y, Van den Bruel A, Wang J, Langendam M, Verbakel JY, Leeflang MM; Cochrane COVID-19 Diagnostic Test Accuracy Group. Routine laboratory testing to determine if a patient has COVID-19. Cochrane Database Syst Rev. 2020 Nov 19;11:CD013787. doi: 10.1002/14651858.CD013787. PMID: 33211319.
Background: Specific diagnostic tests to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and resulting COVID-19 disease are not always available and take time to obtain results. Routine laboratory markers such