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Month: Ottobre 2020

INSALUTENEWS.IT

Encefalopatia ipossico-ischemica, colpiti più di un milione di neonati all’anno. Il ruolo dell’ipotermia terapeutica

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Broni EK, Eke AC, Vaidya D, Tao X, Northington FJ, Everett AD, Graham EM. Blood biomarkers for neonatal hypoxic-ischemic encephalopathy in the presence and absence of sentinel events. J Perinatol. 2020 Oct 6. doi: 10.1038/s41372-020-00850-5. Epub ahead of print. PMID: 33024259.

Objective: To determine if neonatal serum biomarkers representing different pathways of injury differ for cases of HIE of unknown cause to gain insight into timing and mechanism of injury. Study design: In

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Harris C, Bisquera A, Zivanovic S, Lunt A, Calvert S, Marlow N, Peacock JL, Greenough A. Postnatal dexamethasone exposure and lung function in adolescents born very prematurely. PLoS One. 2020 Aug 7;15(8):e0237080. doi: 10.1371/journal.pone.0237080. PMID: 32764779; PMCID: PMC7413559.

We previously demonstrated corticosteroid administration on the neonatal intensive care unit was associated with reduced lung function at 11 to 14 years of age in children born very prematurely. The

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Annink KV, Meerts L, van der Aa NE, Alderliesten T, Nikkels PGJ, Nijboer CHA, Groenendaal F, de Vries LS, Benders MJNL, Hoebeek FE, Dudink J. Cerebellar injury in term neonates with hypoxic-ischemic encephalopathy is underestimated. Pediatr Res. 2020 Sep 23. doi: 10.1038/s41390-020-01173-z. Epub ahead of print. PMID: 32967002.

Background: Postmortem examinations frequently show cerebellar injury in infants with severe hypoxic-ischemic encephalopathy (HIE), while it is less well visible on MRI. The primary aim was to investigate the correlation

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Billion E, Hadchouel A, Garcelon N, Delacourt C, Drummond D. Intravenous pulses of methylprednisolone for infants with severe bronchopulmonary dysplasia and respiratory support after 3 months of age. Pediatr Pulmonol. 2020 Oct 9. doi: 10.1002/ppul.25109. Epub ahead of print. PMID: 33034950.

Introduction: There are few published data on the efficacy of systemic corticosteroids in preterm infants with very severe forms of bronchopulmonary dysplasia (BPD), requiring respiratory support after 3 months of age.

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van der Heide M, Hulscher JBF, Bos AF, Kooi EMW. Near-infrared spectroscopy as a diagnostic tool for necrotizing enterocolitis in preterm infants. Pediatr Res. 2020 Oct 8. doi: 10.1038/s41390-020-01186-8. Epub ahead of print. PMID: 33036017.van der Heide M, Hulscher JBF, Bos AF, Kooi EMW. Near-infrared spectroscopy as a diagnostic tool for necrotizing enterocolitis in preterm infants. Pediatr Res. 2020 Oct 8. doi: 10.1038/s41390-020-01186-8. Epub ahead of print. PMID: 33036017.

Background: We aimed to investigate whether splanchnic tissue oxygen saturation (rsSO2) measured by near-infrared spectroscopy (NIRS) could contribute to the early diagnosis of necrotizing enterocolitis (NEC). Methods: We retrospectively included infants with

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