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Month: Agosto 2020

Franz AR, Engel C, Bassler D, et al. Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trial. JAMA. 2020;324(6):560-570. doi:10.1001/jama.2020.10690

Importance: Red blood cell transfusions are commonly administered to infants weighing less than 1000 g at birth. Evidence-based transfusion thresholds have not been established. Previous studies have suggested higher rates

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Juul SE, Vu PT, Comstock BA, et al. Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age Neonates: Post Hoc Analysis of a Randomized Clinical Trial [published online ahead of print, 2020 Aug 17]. JAMA Pediatr. 2020;10.1001/jamapediatrics.2020.2271. doi:10.1001/jamapediatrics.2020.2271

Importance: Extremely preterm infants are among the populations receiving the highest levels of transfusions. Erythropoietin has not been recommended for premature infants because most studies have not demonstrated a decrease

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Shikany AR, Landis BJ, Parrott A, et al. A Comprehensive Clinical Genetics Approach to Critical Congenital Heart Disease in Infancy [published online ahead of print, 2020 Jul 24]. J Pediatr. 2020;S0022-3476(20)30964-1. doi:10.1016/j.jpeds.2020.07.065

Objective: To investigate the frequency of genetic diagnoses among infants with critical congenital heart disease (CHD) using a comprehensive cardiovascular genetics approach and to identify genotype-phenotype correlations. Study design: A

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Barrero-Castillero A, Mao W, Stark AR, Miedema D, Pursley DM, Burris HH. Glucose concentrations in enterally fed preterm infants [published online ahead of print, 2020 Aug 5]. J Perinatol. 2020;10.1038/s41372-020-0754-6. doi:10.1038/s41372-020-0754-6

Objectives: Determine the prevalence of glucose concentrations below the Pediatric Endocrine Society (PES) term and late preterm-focused guideline target for mean glucose concentrations (≥70 mg/dL) among preterm NICU infants on

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Ramaswamy VV, Bandyopadhyay T, Nanda D, et al. Efficacy of non-invasive respiratory support modes as post extubation respiratory support in preterm neonates: A Systematic Review and Network Meta-analysis [published online ahead of print, 2020 Aug 5]. Pediatr Pulmonol. 2020;10.1002/ppul.25007. doi:10.1002/ppul.25007

Background: Multiple non-invasive respiratory support (NRS) modalities are used for post extubation support in preterm neonates. Seven NRS modalities were compared – Constant flow CPAP (CF-CPAP) [bubble CPAP; ventilator CPAP],

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Inbal GT, Jacob B, Neta L, Orna SC, Yotam D, Aviv G. The Effect of Vitamin D Administration on Vitamin D Status and Respiratory Morbidity in Late Premature Infants [published online ahead of print, 2020 Aug 5]. Pediatr Pulmonol. 2020;10.1002/ppul.25006. doi:10.1002/ppul.25006

Objective: To assess whether increment of vitamin D daily intake results in improved serum 25 (OH) vitamin D levels and reduced respiratory morbidity in premature infants. Methods: A randomized double-blind

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